Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface

Inactivating mutations in the control of virulence two-component regulatory system (covRS) often account for the hypervirulent phenotype in severe, invasive group A streptococcal (GAS) infections. As CovR represses production of the anti-phagocytic hyaluronic acid capsule, high level capsule product...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Galloway-Peña, Jessica, DebRoy, Sruti, Brumlow, Chelcy, Li, Xiqi, Tran, Truc T., Horstmann, Nicola, Yao, Hui, Chen, Ken, Wang, Fang, Pan, Bih-Fang, Hawke, David H., Thompson, Erika J., Arias, Cesar A., Fowler, Vance G., Bhatti, Micah M., Kalia, Awdhesh, Flores, Anthony R., Shelburne, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281247/
https://ncbi.nlm.nih.gov/pubmed/30517150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207897
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