A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus

Catabolite control protein A (CcpA) is a highly conserved, master regulator of carbon source utilization in gram-positive bacteria, but the CcpA regulon remains ill-defined. In this study we aimed to clarify the CcpA regulon by determining the impact of CcpA-inactivation on the virulence and transcr...

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Vydáno v:Sci Rep
Hlavní autoři: DebRoy, Sruti, Saldaña, Miguel, Travisany, Dante, Montano, Andrew, Galloway-Peña, Jessica, Horstmann, Nicola, Yao, Hui, González, Mauricio, Maass, Alejandro, Latorre, Mauricio, Shelburne, Samuel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007534/
https://ncbi.nlm.nih.gov/pubmed/27580596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32442
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