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Regulatory Rewiring Confers Serotype-Specific Hyper-Virulence in the Human Pathogen Group A Streptococcus

Phenotypic heterogeneity is commonly observed between isolates of a given pathogen. Epidemiological analyses have identified that some serotypes of the group A Streptococcus (GAS) are non-randomly associated with particular disease manifestations. Here, we present evidence that a contributing factor...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Miller, Eric W., Danger, Jessica L., Ramalinga, Anupama B., Horstmann, Nicola, Shelburne, Samuel A., Sumby, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675629/
https://ncbi.nlm.nih.gov/pubmed/26192205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13136
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