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Reactive species balance via GTP cyclohydrolase I regulates glioblastoma growth and tumor initiating cell maintenance

BACKGROUND: Depending on the level, differentiation state, and tumor stage, reactive nitrogen and oxygen species inhibit or increase cancer growth and tumor initiating cell maintenance. The rate-limiting enzyme in a pathway that can regulate reactive species production but has not been thoroughly in...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Tran, Anh Nhat, Walker, Kiera, Harrison, David G, Chen, Wei, Mobley, James, Hocevar, Lauren, Hackney, James R, Sedaka, Randee S, Pollock, Jennifer S, Goldberg, Matthew S, Hambardzumyan, Dolores, Cooper, Sara J, Gillespie, Yancey, Hjelmeland, Anita B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280150/
https://ncbi.nlm.nih.gov/pubmed/29409010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy012
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