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STEM-35. GTP CYCLOHYDROLASE I IN TUMOR INITIATING CELL MAINTENANCE AND GLIOBLASTOMA GROWTH: FUNCTIONS AND MECHANISMS

Glioblastoma (GBM), or grade IV astrocytoma, is a deadly disease due in part to the high degree of intratumoral heterogeneity that contributes to treatment failures. One cellular subset enriched for the capacity to propagate tumor growth and promote therapeutic resistance is brain tumor initiating c...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Tran, Anh, Walker, Kiera, Harrison, David, Chen, Wei, Mobley, James, Hocevar, Lauren, Hackney, James, Sedaka, Randee, Pollock, Jennifer, Darley-Usmar, Victor, Cooper, Sara, Gillespie, Yancey, Hjelmeland, Anita
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691898/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.949
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