STEM-35. GTP CYCLOHYDROLASE I IN TUMOR INITIATING CELL MAINTENANCE AND GLIOBLASTOMA GROWTH: FUNCTIONS AND MECHANISMS

Glioblastoma (GBM), or grade IV astrocytoma, is a deadly disease due in part to the high degree of intratumoral heterogeneity that contributes to treatment failures. One cellular subset enriched for the capacity to propagate tumor growth and promote therapeutic resistance is brain tumor initiating c...

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Publicado no:Neuro Oncol
Main Authors: Tran, Anh, Walker, Kiera, Harrison, David, Chen, Wei, Mobley, James, Hocevar, Lauren, Hackney, James, Sedaka, Randee, Pollock, Jennifer, Darley-Usmar, Victor, Cooper, Sara, Gillespie, Yancey, Hjelmeland, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691898/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.949
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