Reactive species balance via GTP cyclohydrolase I regulates glioblastoma growth and tumor initiating cell maintenance

BACKGROUND: Depending on the level, differentiation state, and tumor stage, reactive nitrogen and oxygen species inhibit or increase cancer growth and tumor initiating cell maintenance. The rate-limiting enzyme in a pathway that can regulate reactive species production but has not been thoroughly in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Tran, Anh Nhat, Walker, Kiera, Harrison, David G, Chen, Wei, Mobley, James, Hocevar, Lauren, Hackney, James R, Sedaka, Randee S, Pollock, Jennifer S, Goldberg, Matthew S, Hambardzumyan, Dolores, Cooper, Sara J, Gillespie, Yancey, Hjelmeland, Anita B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Basic and Translational Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280150/
https://ncbi.nlm.nih.gov/pubmed/29409010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy012
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