Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3

Patients suffering from chronic kidney disease (CKD) are at a 20-fold higher risk of dying due to cardiovascular diseases (CVDs), primarily thrombosis following vascular injury. CKD is connected with retention of uremic toxins, especially indoxyl sulfate (IS), which are currently considered as a non...

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Detaylı Bibliyografya
Yayımlandı:Front Physiol
Asıl Yazarlar: Karbowska, Malgorzata, Kaminski, Tomasz W., Znorko, Beata, Domaniewski, Tomasz, Misztal, Tomasz, Rusak, Tomasz, Pryczynicz, Anna, Guzinska-Ustymowicz, Katarzyna, Pawlak, Krystyna, Pawlak, Dariusz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Physiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279869/
https://ncbi.nlm.nih.gov/pubmed/30546314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01623
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