Indoxyl Sulfate Promotes Arterial Thrombosis in Rat Model via Increased Levels of Complex TF/VII, PAI-1, Platelet Activation as Well as Decreased Contents of SIRT1 and SIRT3

Patients suffering from chronic kidney disease (CKD) are at a 20-fold higher risk of dying due to cardiovascular diseases (CVDs), primarily thrombosis following vascular injury. CKD is connected with retention of uremic toxins, especially indoxyl sulfate (IS), which are currently considered as a non...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Physiol
Prif Awduron: Karbowska, Malgorzata, Kaminski, Tomasz W., Znorko, Beata, Domaniewski, Tomasz, Misztal, Tomasz, Rusak, Tomasz, Pryczynicz, Anna, Guzinska-Ustymowicz, Katarzyna, Pawlak, Krystyna, Pawlak, Dariusz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Physiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279869/
https://ncbi.nlm.nih.gov/pubmed/30546314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01623
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