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Single-cell mutation identification via phylogenetic inference

Reconstructing the evolution of tumors is a key aspect towards the identification of appropriate cancer therapies. The task is challenging because tumors evolve as heterogeneous cell populations. Single-cell sequencing holds the promise of resolving the heterogeneity of tumors; however, it has its o...

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Publicado en:Nat Commun
Autores principales: Singer, Jochen, Kuipers, Jack, Jahn, Katharina, Beerenwinkel, Niko
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279798/
https://ncbi.nlm.nih.gov/pubmed/30514897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07627-7
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