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Management of Patients with Acute Methotrexate Nephrotoxicity with High-Dose Leucovorin
BACKGROUND: Acute kidney injury complicating high-dose methotrexate therapy increases the risk for severe mucositis, myelosuppression, and death. It is unclear whether high-dose leucovorin and supportive therapy without the use of glucarpidase can reduce toxicity from high-dose methotrexate. STUDY D...
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| 出版年: | Pharmacotherapy |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279619/ https://ncbi.nlm.nih.gov/pubmed/29863765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.2145 |
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