Clinically relevant and minimally invasive tumor surveillance of pediatric diffuse midline gliomas using patient derived liquid biopsy

PURPOSE: Pediatric DMGs are highly malignant tumors with poor clinical outcomes. Over 70% of DMG patients harbor the histone 3 p.K27M (H3K27M) mutation, which correlates with a poorer clinical outcome, and is also used as a criterion for enrollment in clinical trials. Because complete surgical resec...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Panditharatna, Eshini, Kilburn, Lindsay B., Aboian, Mariam S., Kambhampati, Madhuri, Gordish-Dressman, Heather, Magge, Suresh N., Gupta, Nalin, Myseros, John S., Hwang, Eugene I., Kline, Cassie, Crawford, John R., Warren, Katherine E., Cha, Soonmee, Liang, Winnie S., Berens, Michael E., Packer, Roger J., Resnick, Adam C., Prados, Michael, Mueller, Sabine, Nazarian, Javad
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279526/
https://ncbi.nlm.nih.gov/pubmed/30322880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1345
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