Clinically relevant and minimally invasive tumor surveillance of pediatric diffuse midline gliomas using patient derived liquid biopsy

PURPOSE: Pediatric DMGs are highly malignant tumors with poor clinical outcomes. Over 70% of DMG patients harbor the histone 3 p.K27M (H3K27M) mutation, which correlates with a poorer clinical outcome, and is also used as a criterion for enrollment in clinical trials. Because complete surgical resec...

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Publicat a:Clin Cancer Res
Autors principals: Panditharatna, Eshini, Kilburn, Lindsay B., Aboian, Mariam S., Kambhampati, Madhuri, Gordish-Dressman, Heather, Magge, Suresh N., Gupta, Nalin, Myseros, John S., Hwang, Eugene I., Kline, Cassie, Crawford, John R., Warren, Katherine E., Cha, Soonmee, Liang, Winnie S., Berens, Michael E., Packer, Roger J., Resnick, Adam C., Prados, Michael, Mueller, Sabine, Nazarian, Javad
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279526/
https://ncbi.nlm.nih.gov/pubmed/30322880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1345
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