ロード中...

Dual targeting of aurora kinases with AMG 900 exhibits potent preclinical activity against acute myeloid leukemia with distinct post-mitotic outcomes

Aurora kinase A and B have essential and non-overlapping roles in mitosis, with elevated expression in a subset of human cancers, including acute myeloid leukemia (AML). In this study, pan-aurora kinase inhibitor (AKI) AMG 900 distinguishes itself as an anti-leukemic agent that is more uniformly pot...

詳細記述

保存先:
書誌詳細
出版年:Mol Cancer Ther
主要な著者: Payton, Marc, Cheung, Hung-Kam, Ninniri, Maria Stefania S., Marinaccio, Christian, Wayne, William C., Hanestad, Kelly, Crispino, John D., Juan, Gloria, Coxon, Angela
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279493/
https://ncbi.nlm.nih.gov/pubmed/30266802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0186
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!