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An Aurora kinase inhibitor, AMG900, inhibits glioblastoma cell proliferation by disrupting mitotic progression

The Aurora kinase family of serine/threonine protein kinases comprises Aurora A, B, and C and plays an important role in mitotic progression. Several inhibitors of Aurora kinase have been developed as anti‐cancer therapeutics. Here, we examined the effects of a pan‐Aurora kinase inhibitor, AMG900, a...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Ryu, Jaewook, Pyo, Jaehyuk, Lee, Chang‐Woo, Kim, Ja‐Eun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246935/
https://ncbi.nlm.nih.gov/pubmed/30221846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1771
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