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Biodistribution, pharmacokinetics, and nuclear imaging studies of (111)In-labeled rGel/BLyS fusion toxin in SCID mice bearing B-cell lymphoma

PURPOSE: We examine the biodistribution and pharmacokinetics of (111)In-labeled rGel/BLyS, a gelonin toxin (rGel)-B lymphocyte stimulator (BLyS) fusion protein. MATERIALS AND METHODS: rGel/BLyS was labeled with In-111 through DTPA with a labeling efficiency >95%. Biodistribution/imaging studies w...

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Détails bibliographiques
Publié dans:Mol Imaging Biol
Auteurs principaux: Wen, Xiaoxia, Lyu, Mi-Ae, Zhang, Rui, Lu, Wei, Huang, Qian, Liang, Dong, Rosenblum, Michael G., Li, Chun
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279425/
https://ncbi.nlm.nih.gov/pubmed/20686856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0391-0
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