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BLyS and APRIL in rheumatoid arthritis

The cytokines B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL) enhance autoimmune disease by sustaining B cell activation. In RA, B cells contribute to the formation of 3 functionally distinct types of lymphoid microarchitectures in the inflamed synovium: ectopic GCs; T cel...

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Detalhes bibliográficos
Main Authors: Seyler, Thorsten M., Park, Yong W., Takemura, Seisuke, Bram, Richard J., Kurtin, Paul J., Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257539/
https://ncbi.nlm.nih.gov/pubmed/16239971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25265
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