Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy

Rationale: Regulatory T cells (Treg) play a pivotal role in the immunosuppressive tumor micro-environment in cancer, including mesothelioma. Recently, the combination of autologous tumor lysate-pulsed dendritic cells (DC) and metronomic cyclophosphamide (mCTX) was reported as a feasible and well-tol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Noordam, Lisanne, Kaijen, Margaretha E.H., Bezemer, Koen, Cornelissen, Robin, Maat, Lex A.P.W.M., Hoogsteden, Henk C., Aerts, Joachim G.J.V., Hendriks, Rudi W., Hegmans, Joost P.J.J, Vroman, Heleen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279421/
https://ncbi.nlm.nih.gov/pubmed/30524884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1474318
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados