Ratio of Intratumoral Macrophage Phenotypes Is a Prognostic Factor in Epithelioid Malignant Pleural Mesothelioma

HYPOTHESIS: The tumor micro-environment and especially the different macrophage phenotypes appear to be of great influence on the behavior of multiple tumor types. M1 skewed macrophages possess anti-tumoral capacities, while the M2 polarized macrophages have pro-tumoral capacities. We analyzed if th...

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Main Authors: Cornelissen, Robin, Lievense, Lysanne A., Maat, Alexander P., Hendriks, Rudi W., Hoogsteden, Henk C., Bogers, Ad J., Hegmans, Joost P., Aerts, Joachim G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156398/
https://ncbi.nlm.nih.gov/pubmed/25192022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106742
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