Ribosome biogenesis factor Ltv1 chaperones the assembly of the small subunit head

The correct assembly of ribosomes from ribosomal RNAs (rRNAs) and ribosomal proteins (RPs) is critical, as indicated by the diseases caused by RP haploinsufficiency and loss of RP stoichiometry in cancer cells. Nevertheless, how assembly of each RP is ensured remains poorly understood. We use yeast...

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Publicat a:J Cell Biol
Autors principals: Collins, Jason C., Ghalei, Homa, Doherty, Joanne R., Huang, Haina, Culver, Rebecca N., Karbstein, Katrin
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279377/
https://ncbi.nlm.nih.gov/pubmed/30348748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804163
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