Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

Casein kinase 1δ/ε (CK1δ/ε) and their yeast homologue Hrr25 are essential for cell growth. Further, CK1δ is overexpressed in several malignancies, and CK1δ inhibitors have shown promise in several preclinical animal studies. However, the substrates of Hrr25 and CK1δ/ε that are necessary for cell gro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Ghalei, Homa, Schaub, Franz X., Doherty, Joanne R., Noguchi, Yoshihiko, Roush, William R., Cleveland, John L., Stroupe, M. Elizabeth, Karbstein, Katrin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2015
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362465/
https://ncbi.nlm.nih.gov/pubmed/25778921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409056
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