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A bilobal model of Ca(2+)-dependent inactivation to probe the physiology of L-type Ca(2+) channels

L-type calcium channels (LTCCs) are critical elements of normal cardiac function, playing a major role in orchestrating cardiac electrical activity and initiating downstream signaling processes. LTCCs thus use feedback mechanisms to precisely control calcium (Ca(2+)) entry into cells. Of these, Ca(2...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gen Physiol
Prif Awduron: Limpitikul, Worawan B., Greenstein, Joseph L., Yue, David T., Dick, Ivy E., Winslow, Raimond L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279366/
https://ncbi.nlm.nih.gov/pubmed/30470716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812115
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