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Integrated analysis of the immunological and genetic status in and across cancer types: impact of mutational signatures beyond tumor mutational burden

Harnessing the immune system by checkpoint blockade has greatly expanded the therapeutic options for advanced cancer. Since the efficacy of immunotherapies is influenced by the molecular make-up of the tumor and its crosstalk with the immune system, comprehensive analysis of genetic and immunologic...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Budczies, Jan, Seidel, Anja, Christopoulos, Petros, Endris, Volker, Kloor, Matthias, Győrffy, Balázs, Seliger, Barbara, Schirmacher, Peter, Stenzinger, Albrecht, Denkert, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279340/
https://ncbi.nlm.nih.gov/pubmed/30524909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1526613
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