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Integrated analysis of the immunological and genetic status in and across cancer types: impact of mutational signatures beyond tumor mutational burden

Harnessing the immune system by checkpoint blockade has greatly expanded the therapeutic options for advanced cancer. Since the efficacy of immunotherapies is influenced by the molecular make-up of the tumor and its crosstalk with the immune system, comprehensive analysis of genetic and immunologic...

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Podrobná bibliografie
Vydáno v:Oncoimmunology
Hlavní autoři: Budczies, Jan, Seidel, Anja, Christopoulos, Petros, Endris, Volker, Kloor, Matthias, Győrffy, Balázs, Seliger, Barbara, Schirmacher, Peter, Stenzinger, Albrecht, Denkert, Carsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279340/
https://ncbi.nlm.nih.gov/pubmed/30524909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1526613
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