Monosodium Glutamate Reduces (68)Ga-PSMA-11 Uptake in Salivary Glands and Kidneys in a Preclinical Prostate Cancer Model

We evaluated the ability of monosodium glutamate (MSG) to reduce salivary and kidney uptake of a prostate-specific membrane antigen (PSMA) radioligand without affecting tumor uptake. Methods: LNCaP tumor–bearing mice were intraperitoneally injected with MSG (657, 329, or 164 mg/kg) or phosphate-buff...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Nucl Med
Auteurs principaux: Rousseau, Etienne, Lau, Joseph, Kuo, Hsiou-Ting, Zhang, Zhengxing, Merkens, Helen, Hundal-Jabal, Navjit, Colpo, Nadine, Lin, Kuo-Shyan, Bénard, François
Format: Artigo
Langue:Inglês
Publié: Society of Nuclear Medicine 2018
Sujets:
Theranostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278899/
https://ncbi.nlm.nih.gov/pubmed/30097503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.215350
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