Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography

BACKGROUND: The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more binding sites on the cell surface, resulting in higher tumo...

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Udgivet i:EJNMMI Radiopharm Chem
Main Authors: Dude, Iulia, Zhang, Zhengxing, Rousseau, Julie, Hundal-Jabal, Navjit, Colpo, Nadine, Merkens, Helen, Lin, Kuo-Shyan, Bénard, François
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824694/
https://ncbi.nlm.nih.gov/pubmed/29503845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-017-0023-y
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