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CTLA-4 and PD-1 Control of T-Cell Motility and Migration: Implications for Tumor Immunotherapy

CTLA-4 is a co-receptor on T-cells that controls peripheral tolerance and the development of autoimmunity. Immune check-point blockade (ICB) uses monoclonal antibodies (MAbs) to block the binding of inhibitory receptors (IRs) to their natural ligands. A humanized antibody to CTLA-4 was first approve...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Brunner-Weinzierl, Monika C., Rudd, Christopher E.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277866/
https://ncbi.nlm.nih.gov/pubmed/30542345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02737
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