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Emerging targets in cancer immunotherapy: beyond CTLA-4 and PD-1
Manipulation of co-stimulatory or co-inhibitory checkpoint proteins allows for the reversal of tumor-induced T-cell anergy observed in cancer. The field has gained credence given success with CTLA-4 and PD-1 inhibitors. These molecules include immunoglobulin family members and the B7 subfamily as we...
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| Publicado no: | Immunotherapy |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976877/ https://ncbi.nlm.nih.gov/pubmed/26567614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.15.78 |
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