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Chemically Induced Cellular Proteolysis: An Emerging Therapeutic Strategy for Undruggable Targets
Traditionally, small-molecule or antibody-based therapies against human diseases have been designed to inhibit the enzymatic activity or compete for the ligand binding sites of pathological target proteins. Despite its demonstrated effectiveness, such as in cancer treatment, this approach is often l...
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| Publicado no: | Mol Cells |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Molecular and Cellular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277563/ https://ncbi.nlm.nih.gov/pubmed/30486612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2018.0372 |
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