Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice

Liver sinusoidal endothelial cells (LSECs) have great capacity for liver regeneration, and this capacity can easily switch to profibrotic phenotype, which is still poorly understood. In this study, we elucidated a potential target in LSECs for regenerative treatment that can bypass fibrosis during c...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Ther
Κύριοι συγγραφείς: Lao, Yuanxiang, Li, Yanyan, Zhang, Ping, Shao, Qianqian, Lin, Weiran, Qiu, Bintao, Lv, Yongzhuang, Tang, Lichun, Su, Shishuai, Zhang, Hongyu, Tian, Chunyan, Sun, Aihua, Wei, Handong, Zhang, Pumin, Wu, Yan, Jiang, Ying, He, Fuchu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Gene & Cell Therapy 2018
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277559/
https://ncbi.nlm.nih.gov/pubmed/30266653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.08.016
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