Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice

Liver sinusoidal endothelial cells (LSECs) have great capacity for liver regeneration, and this capacity can easily switch to profibrotic phenotype, which is still poorly understood. In this study, we elucidated a potential target in LSECs for regenerative treatment that can bypass fibrosis during c...

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Publicado en:Mol Ther
Autores principales: Lao, Yuanxiang, Li, Yanyan, Zhang, Ping, Shao, Qianqian, Lin, Weiran, Qiu, Bintao, Lv, Yongzhuang, Tang, Lichun, Su, Shishuai, Zhang, Hongyu, Tian, Chunyan, Sun, Aihua, Wei, Handong, Zhang, Pumin, Wu, Yan, Jiang, Ying, He, Fuchu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2018
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277559/
https://ncbi.nlm.nih.gov/pubmed/30266653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.08.016
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