Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice

Liver sinusoidal endothelial cells (LSECs) have great capacity for liver regeneration, and this capacity can easily switch to profibrotic phenotype, which is still poorly understood. In this study, we elucidated a potential target in LSECs for regenerative treatment that can bypass fibrosis during c...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Mol Ther
المؤلفون الرئيسيون: Lao, Yuanxiang, Li, Yanyan, Zhang, Ping, Shao, Qianqian, Lin, Weiran, Qiu, Bintao, Lv, Yongzhuang, Tang, Lichun, Su, Shishuai, Zhang, Hongyu, Tian, Chunyan, Sun, Aihua, Wei, Handong, Zhang, Pumin, Wu, Yan, Jiang, Ying, He, Fuchu
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Gene & Cell Therapy 2018
الموضوعات:
Original Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277559/
https://ncbi.nlm.nih.gov/pubmed/30266653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.08.016
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