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MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
The role of mitochondria dynamics and its molecular regulators remains largely unknown during naïve-to-primed pluripotent cell interconversion. Here we report that mitochondrial MTCH2 is a regulator of mitochondrial fusion, essential for the naïve-to-primed interconversion of murine embryonic stem c...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277412/ https://ncbi.nlm.nih.gov/pubmed/30510213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07519-w |
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