Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders()()

OBJECTIVES: Remodeling of the extracellular matrix (ECM) is a key event in different lung disorders, such as fibrosis and cancer. The most common cell type in the connective tissue is fibroblasts, which transdifferentiate into myofibroblasts upon activation. All myofibroblasts express α-SMA, which h...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Holm Nielsen, Signe, Willumsen, Nicholas, Leeming, Diana Julie, Daniels, Samuel Joseph, Brix, Susanne, Karsdal, Morten Asser, Genovese, Federica, Nielsen, Mette Juul
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277250/
https://ncbi.nlm.nih.gov/pubmed/30504086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.11.004
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