Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders()()

OBJECTIVES: Remodeling of the extracellular matrix (ECM) is a key event in different lung disorders, such as fibrosis and cancer. The most common cell type in the connective tissue is fibroblasts, which transdifferentiate into myofibroblasts upon activation. All myofibroblasts express α-SMA, which h...

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Опубликовано в: :Transl Oncol
Главные авторы: Holm Nielsen, Signe, Willumsen, Nicholas, Leeming, Diana Julie, Daniels, Samuel Joseph, Brix, Susanne, Karsdal, Morten Asser, Genovese, Federica, Nielsen, Mette Juul
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press 2018
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Original article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277250/
https://ncbi.nlm.nih.gov/pubmed/30504086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.11.004
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