Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling

BACKGROUND: During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degradation of elastin. We selected specific elastin fragments generated by NE for ant...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Kristensen, Jacob H, Karsdal, Morten A, Sand, Jannie MB, Willumsen, Nicholas, Diefenbach, Claudia, Svensson, Birte, Hägglund, Per, Oersnes-Leeming, Diana J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426538/
https://ncbi.nlm.nih.gov/pubmed/25935650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0048-5
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