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RNA virus evasion of nonsense-mediated decay

Nonsense-mediated decay (NMD) is a host RNA control pathway that removes aberrant transcripts with long 3’ untranslated regions (UTRs) due to premature termination codons (PTCs) that arise through mutation or defective splicing. To maximize coding potential, RNA viruses often contain internally loca...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: May, Jared P., Yuan, Xuefeng, Sawicki, Erika, Simon, Anne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277124/
https://ncbi.nlm.nih.gov/pubmed/30452463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007459
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