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More is not always better: hyperglutamylation leads to neurodegeneration

Post‐translational modifications of tubulin can regulate the dynamics and mechanical properties of microtubules and their interactions with different proteins, such as molecular motors. Two studies now demonstrate that excessive accumulation of a specific modification, polyglutamylation, leads to ne...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Akhmanova, Anna, Hoogenraad, Casper C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276874/
https://ncbi.nlm.nih.gov/pubmed/30470721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101023
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