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More is not always better: hyperglutamylation leads to neurodegeneration
Post‐translational modifications of tubulin can regulate the dynamics and mechanical properties of microtubules and their interactions with different proteins, such as molecular motors. Two studies now demonstrate that excessive accumulation of a specific modification, polyglutamylation, leads to ne...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6276874/ https://ncbi.nlm.nih.gov/pubmed/30470721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101023 |
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