Controlling the mitochondrial antisense – role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance

Transcription of the human mitochondrial genome produces a vast amount of non-coding antisense RNAs. These RNA species can form G-quadraplexes (G4), which affect their decay. We found that the mitochondrial degradosome, a complex of RNA helicase SUPV3L1 (best known as SUV3) and the ribonuclease PNPT...

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Udgivet i:Mol Cell Oncol
Main Authors: Pietras, Zbigniew, Wojcik, Magdalena A., Borowski, Lukasz S., Szewczyk, Maciej, Kulinski, Tomasz M., Cysewski, Dominik, Stepien, Piotr P., Dziembowski, Andrzej, Szczesny, Roman J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276855/
https://ncbi.nlm.nih.gov/pubmed/30525095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1516452
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