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Dedicated surveillance mechanism controls G-quadruplex forming non-coding RNAs in human mitochondria
The GC skew in vertebrate mitochondrial genomes results in synthesis of RNAs that are prone to form G-quadruplexes (G4s). Such RNAs, although mostly non-coding, are transcribed at high rates and are degraded by an unknown mechanism. Here we describe a dedicated mechanism of degradation of G4-contain...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028389/ https://ncbi.nlm.nih.gov/pubmed/29967381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05007-9 |
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