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Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance

The mechanism of human mitochondrial RNA turnover and surveillance is still a matter of debate. We have obtained a cellular model for studying the role of hSuv3p helicase in human mitochondria. Expression of a dominant-negative mutant of the hSUV3 gene which encodes a protein with no ATPase or helic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Szczesny, Roman J., Borowski, Lukasz S., Brzezniak, Lien K., Dmochowska, Aleksandra, Gewartowski, Kamil, Bartnik, Ewa, Stepien, Piotr P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800237/
https://ncbi.nlm.nih.gov/pubmed/19864255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp903
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