Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

CDH1 and PIK3CA are the two most frequently mutated genes in invasive lobular carcinoma (ILC) of the breast. Transcription profiling has identified molecular subtypes for ILC, one of which, immune-related (IR), is associated with gene expression linked to lymphocyte and macrophage infiltration. Here...

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Udgivet i:Cell Rep
Main Authors: An, Yeji, Adams, Jessica R., Hollern, Daniel P., Zhao, Anthony, Chang, Stephen G., Gams, Miki S., Chung, Philip E.D., He, Xiaping, Jangra, Rhea, Shah, Juhi S., Yang, Joanna, Beck, Lauren A., Raghuram, Nandini, Kozma, Katelyn J., Loch, Amanda J., Wang, Wei, Fan, Cheng, Done, Susan J., Zacksenhaus, Eldad, Guidos, Cynthia J., Perou, Charles M., Egan, Sean E.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276789/
https://ncbi.nlm.nih.gov/pubmed/30332649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.056
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