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Common and distinct features of mammary tumors driven by Pten-deletion or activating Pik3ca mutation
PTEN loss and PIK3CA activation both promote the accumulation of phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3). While these proteins also have distinct biochemical functions, beyond the regulation of PIP3, little is known about the consequences of these differences in vivo. Here, we directly c...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891026/ https://ncbi.nlm.nih.gov/pubmed/26814435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6985 |
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