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Germline CDH1 mutations in bilateral lobular carcinoma in situ

BACKGROUND: Invasive lobular breast cancer (ILC) and lobular carcinoma in situ (LCIS) are characterised by loss of E-cadherin expression. However germline CDH1 mutations are rare in cases of ILC with no family history of hereditary diffuse gastric cancer (HDGC) and have not been described in women w...

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Bibliografiske detaljer
Main Authors: Petridis, C, Shinomiya, I, Kohut, K, Gorman, P, Caneppele, M, Shah, V, Troy, M, Pinder, S E, Hanby, A, Tomlinson, I, Trembath, R C, Roylance, R, Simpson, M A, Sawyer, E J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929874/
https://ncbi.nlm.nih.gov/pubmed/24366306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.792
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