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Germline CDH1 mutations in bilateral lobular carcinoma in situ

BACKGROUND: Invasive lobular breast cancer (ILC) and lobular carcinoma in situ (LCIS) are characterised by loss of E-cadherin expression. However germline CDH1 mutations are rare in cases of ILC with no family history of hereditary diffuse gastric cancer (HDGC) and have not been described in women w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petridis, C, Shinomiya, I, Kohut, K, Gorman, P, Caneppele, M, Shah, V, Troy, M, Pinder, S E, Hanby, A, Tomlinson, I, Trembath, R C, Roylance, R, Simpson, M A, Sawyer, E J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929874/
https://ncbi.nlm.nih.gov/pubmed/24366306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.792
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