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IGF-1 and pAKT Signalling Promote Hippocampal CA1 Neuronal Survival Following Injury to Dentate Granule Cells.

Insulin-like growth factor-1 (IGF-1) protects neurons from apoptosis and in vivo offers neuroprotective support to hippocampal CA1 pyramidal neurons following ischemia or seizure. IGF-1 signals through IGF-1 receptors activating phosphytidylinositol 3-kinase (PI3K)/Akt or pMAPK pathways. IGF-1 can b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurotox Res
Egile Nagusiak: Wine, Robert N., McPherson, Christopher A., Harry, G. Jean
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276784/
https://ncbi.nlm.nih.gov/pubmed/19526277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-009-9060-y
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