Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways

OBJECTIVE: The goal of this study was to determine the effects of beraprost sodium (BPS) preconditioning on hepatic ischemia-reperfusion (IR) injury and its underlying mechanisms of action. MATERIALS AND METHODS: Mice were randomly divided into sham, IR, IR+BPS (50 µg/kg), and IR+BPS (100 µg/kg) gro...

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Enregistré dans:
Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Deng, Jingfan, Feng, Jiao, Liu, Tong, Lu, Xiya, Wang, Wenwen, Liu, Ning, Lv, Yang, Liu, Qing, Guo, Chuanyong, Zhou, Yingqun
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276616/
https://ncbi.nlm.nih.gov/pubmed/30568428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S182292
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