Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway

BACKGROUND: Hepatic ischemia reperfusion (IR) injury is a common phenomenon in transplantation or trauma. The aim of the present study was to determine the protective effect of quercetin (QE) on hepatic IR injury via the ERK/NF-κB pathway. METHODS: Mice were randomized into the sham, IR, QE100 + IR,...

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Enregistré dans:
Détails bibliographiques
Publié dans:Gastroenterol Res Pract
Auteurs principaux: Wu, Liwei, Zhang, Qinghui, Dai, Weiqi, Li, Sainan, Feng, Jiao, Li, Jingjing, Liu, Tong, Xu, Shizan, Wang, Wenwen, Lu, Xiya, Yu, Qiang, Chen, Kan, Xia, Yujing, Lu, Jie, Zhou, Yingqun, Fan, Xiaoming, Guo, Chuanyong
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662816/
https://ncbi.nlm.nih.gov/pubmed/29123547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9724217
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