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V-ATPases and osteoclasts: ambiguous future of V-ATPases inhibitors in osteoporosis
Vacuolar ATPases (V-ATPases) play a critical role in regulating extracellular acidification of osteoclasts and bone resorption. The deficiencies of subunit a3 and d2 of V-ATPases result in increased bone density in humans and mice. One of the traditional drug design strategies in treating osteoporos...
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| Vydáno v: | Theranostics |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Ivyspring International Publisher
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6276090/ https://ncbi.nlm.nih.gov/pubmed/30555553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.28391 |
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