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Regulating Apoptosis by Degradation: The N-End Rule-Mediated Regulation of Apoptotic Proteolytic Fragments in Mammalian Cells

A pivotal hallmark of some cancer cells is the evasion of apoptotic cell death. Importantly, the initiation of apoptosis often results in the activation of caspases, which, in turn, culminates in the generation of proteolytically-activated protein fragments with potentially new or altered roles. Rec...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Eldeeb, Mohamed A., Fahlman, Richard P., Esmaili, Mansoore, Ragheb, Mohamed A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274719/
https://ncbi.nlm.nih.gov/pubmed/30384441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113414
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