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Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells

Background: Several mechanisms of action have been proposed to explain the apparent antineoplastic functions of metformin, many of which are observed at high concentrations that may not be reflective of achievable tissue concentrations. We propose that metformin at low concentrations functions to in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Schexnayder, Chandler, Broussard, Kiera, Onuaguluchi, Demitrius, Poché, Anthony, Ismail, Moamen, McAtee, LeFontae, Llopis, Shawn, Keizerweerd, Amber, McFerrin, Harris, Williams, Christopher
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274682/
https://ncbi.nlm.nih.gov/pubmed/30469399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113692
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